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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
免疫学的贡献者
Immunology
immunoreceptor 基于酪氨酸激活图案
生物学; 免疫学
T、 B 细胞抗原受体是与跨膜分子与 immunoreceptor 基于酪氨酸激活图案 (ITAMs) 在其细胞质的域相关联。这些含酪氨酸的图案是酪氨酸磷酸化和结社与酪氨酸激酶和其他参与受体信号转导的酪氨酸结合环的站点。Immunoreceptor 基于酪氨酸抑制图案 (ITIMs),招聘到受体站点删除添加的酪氨酸激酶的磷酸组的磷酸 相关的主题与反对的影响。 ...